3 Myths About Spravato (Esketamine)

3 Myths About Spravato (Esketamine)

Let’s take a closer look at some common myths about Spravato and separate fact from fiction.

Spravato (esketamine) has emerged as a groundbreaking treatment option for individuals struggling with treatment-resistant depression.

While its efficacy has garnered attention, various myths have also surfaced, leading to confusion and (potentially harmful) misconceptions.

Let’s take a closer look at some common myths about Spravato and separate fact from fiction!

Read on for 3 myths about Spravato (esketamine):

Myth #1: Spravato is “just another antidepressant”.

REALITY: While Spravato is classified as a fast-acting antidepressant, it operates differently than traditional antidepressants. Most antidepressants target serotonin or norepinephrine levels, taking weeks to months to show effects.

In contrast, Spravato works on the glutamate system, which can lead to rapid improvements in mood. Many patients report feeling relief within hours, making it a unique option for those who have not found success with conventional treatments.

Myth #2: Spravato is risky and addictive.

REALITY: Concerns about the safety and potential for abuse of Spravato stem from its classification as a Schedule III controlled substance. While it can cause side effects—similar to those seen with ketamine— in a small number of patients, when used as prescribed and administered under medical supervision, the risk of addiction is low.

Healthcare providers monitor patients closely during treatment to mitigate risks and ensure safe administration.

Myth #3: Spravato is a total “cure” for depression.

REALITY: While Spravato can provide significant relief for many individuals, it is not a cure for depression. Like other treatments, it may help manage symptoms but doesn’t eliminate the underlying condition.

Patients typically engage in a comprehensive treatment plan that may include psychotherapy, lifestyle changes, and ongoing medication management to maintain their mental health over the long term.

 


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